Description:Sterile recombinant imipenem hydrolase expressed in E.coli is used in the test of sterility and microbial limit of β-lactam antibiotics, especially imipenem.
Introduction
INDUMY® Imipenem Hydrolase is a kind of recombinant carbapenemase expressed in E.col and purfied to high homogeneity with high activity. It hydrolyse the β-lactam ring of imipenem antibiotics and inactivate the antibiotics. This enzyme can inactivate β-lactam antibiotics such as ceftriaxon, cefazolin, ceftazidime, cefoxitin, cefepime, cefuroxime, cefotaxime, oxacillin, imipenem, and meropenem.
Appearance
Clear and colorless liquid.
Package
5 IU/vial.
Unit definition：
One unit of imipenem hydrolase activity is defined as the amount of preparation which hydrolyse 1μmol imipenem in one minute at 25℃ and pH7.0. That is equivalent to 0.3mg imipenem.
The test of sterility
It is negtive of the sterility test.
Usage
The test of sterility and microbial limit of β-lactam antibiotics, especially imipenem.
Store
Stable at -20℃ for more than one year.
