Description

        Metallo-β-Lactamase (MBL) is produced by genetic engineering technology. It is expressed in recombinant E.coli and highly purified to homogeneity. The enzyme can hydrolyze β-Lactam ring of lactam antibiotics, especially that in monocyclic β-lactams. The hydrolysis makes the antibiotics lose their anti-microbial activity. The product has specificity and can hydrolyze imipenem, meropenem, ertapenem and other antibiotics β-lactam ring. It also can hydrolyze penicillin sodium, cefixime, cefoperazone, cefotaxime, ceftriaxone, cefoxitin, etc. After radiation, the lyophilized powder is finally sterilized.

Appearance

        White or pain white lyophilized powder.

Package

        2 MU/bottle

Specifications

        One unit is defined as the amount of enzyme required to hydrolyze one biological unit of penicillin G in one hour at pH 7.0, 37˚C.

Application

Note

           0.1mM Mg2+and 0.1mM Zn2+play an important role in the enzyme activity;  Avoid violent oscillation, and prevent a large number of bubbles during resuspension. 

          Stable at 2~8℃for more than two years since report.

Catalog #

          DU-13-0001