Description

        Thermostable cephalosporinase is a kind of Type II β-Lactamase. It can hydrolyze β-lactam antibiotic β-lactam ring and makes it loses its anti-microbial activity. This product is a recombinant enzyme obtained by genetic engineering technology. Through the construction of a highly efficient expression E.coli strain and fermentation, purification, a high purity and high activity product is obtained. It is characterized by specificity and effectively hydrolyze β-Lactam ring of cephalosporins, cefadroxil, cefradine, cefaclor, cefuroxime, cefixime, cefoperazone, cefotaxime, ceftriaxone, cefoxitin, cefepime, etc.

        When the enzyme is kept at 50℃ for 4 hours, the residual enzyme activity reaches more than 90%. It has obvious advantages and is very suitable for adding agar plate medium.

Appearance

        White or pain white lyophilized powder.

Package

        5 MU/bottle

Specifications

        One unit is defined as the amount of enzyme required to hydrolyze one biological unit of penicillin G in one hour at pH 7.0, 37˚C.

Application

        Environmental monitoring of antibiotic manufacturing areas;

        Sterility testing of bulk Antibiotics;

        Testing sterility of blood cultures;

        Testing for β-lactam contamination of drugs.

Stability

        Stable at 2~8℃for more than two years since report.

Catalog #

        DU-19-001